Das "Handbuch der Balneologie und medizinischen Klimatologie" vermittelt Ihnen das moderne Grundlagen- und Praxiswissen fur den optimalen, wissenschaftlich fundierten Einsatz kurortmedizinischer Behandlungsmassnahmen.
o systematisch und anwendungsgerecht gegliedert
o prazise, verstandlich und straff formuliert
o mit anschaulichen Abbildungen und instruktiven Tabellen
Der aktuelle Wissensstand in einzigartiger Vollstandigkeit
o Physiologische Grundlagen der Therapie und therapeutische Wirkprinzipien
o Heilmitteldarstellung und Anwendungstechnik
o Indikationen und Therapiepraxis im ganzheitlichen Gesamtkonzept
Lehrbuch, Nachschlagewerk und Handbuch gleichzeitig:
* mit den Grundlagen fur die qualifizierte Aus- und Weiterbildung,
* mit klaren therapeutischen Richtlinien fur den individuellen Behandlungsplan Ihrer Patienten.
Die tagliche Sicherheit fur Ihr therapeutisches Handeln.

This major new edition fulfils the need for a single-volume, up-to-date information resource on the etiology, pathogenesis, diagnosis and treatment of diseases of skeletal muscles, including the muscular dystrophies, mitochondrial myopathies, metabolic myopathies, ion channel disorders, and dysimmune myopathies. As background to the clinical coverage, relevant information on advances in molecular and developmental biology, immunopathology, mitochondrial biology, ion-channel dynamics, cell membrane and signal transduction science, and imaging technology is summarized. Combining essential new knowledge with the fundamentals of history-taking and clinical examination, this extensively illustrated book will continue to be the mainstay for practising physicians and biomedical scientists concerned with muscle disease. Regular updates on the clinical and basic science aspects of muscle disease - written mainly by rising stars of myology - will be published on an accompanying website.

Successfully correlate electrodiagnostic findings and neuromuscular ultrasound with key clinical findings with Electromyography and Neuromuscular Disorders, 4th Edition. This popular text is the go-to resource for clinicians at all levels of experience who have an interest in neuromuscular medicine, including those studying for the AANEM board exam. An easy-to-read writing style, abundant case studies, and learning features online help you master the electrodiagnostic evaluation and improve safety and accuracy. Helps you diagnose neuromuscular disorders more quickly and accurately, and correlate electromyographic and clinical findings. Explains complex subject matter in an easy-to-understand, user-friendly manner. Includes dozens of detailed, cross-sectional anatomy drawings to ensure correct EMG needle placement and avoid neurovascular injuries. Features new chapters on Neuromuscular Ultrasound, as well as incorporating neuromuscular ultrasound in the evaluation of clinical neuromuscular disorders along with electrodiagnostic studies in many of the clinical chapters. Provides up-to-date information on iatrogenic complications of electrodiagnostic studies and newly defined genetic neuromuscular conditions. Includes online access to more than 70 videos that allow you to see and hear the EMG waveforms discussed in the text, as well as a convenient "Test Your Knowledge" module. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Musculoskeletal MRI covers the entire musculoskeletal system and related conditions, both common and rare. The text is neatly divided into sections based on the major anatomic divisions. Each section discusses anatomic subdivisions or joints, keeping sections on normal anatomy and pathologic findings close to each other, allowing radiologists to easily compare images of normal and pathologic findings. With more than 4000 high-quality MR images, information is presented in an easy-to-read bulleted format, providing the radiologist with all the information required to make an informed diagnosis in the clinical setting. The new edition also includes a complimentary eBook as well as access to image downloads. Comprehensive and user-friendly in its approach, the book provides every radiologist, both consultant and trainee, with increased confidence in their reporting.

The definitive guide to thoracic spine pathologies and state-of-the-art surgical approaches Surgery of the Thoracic Spine: Principles and Techniques by renowned spine surgeons Ali Baaj, Kumar Kakarla, and Han Jo Kim fills a gap in the literature, with content focused solely on pathologies and surgical techniques of the thoracic spine and vertebral column. Starting with a thoughtful discussion on the uniqueness of the thoracic region as it relates to pulmonary function, the richly illustrated textbook covers a full spectrum of topics from biomechanics and anesthetic considerations to neuromonitoring and neuronavigation. With contributions from a cadre of distinguished experts, the book encompasses pathophysiology, surgical techniques, and reconstructive strategies for common degenerative, congenital, oncologic, and traumatic diseases of the thoracic spine. Dedicated chapters cover treatment options for different types of scoliosis, Scheuermann kyphosis, proximal junctional deformity, and posttraumatic deformity. Key Features Treatment of common degenerative conditions including stenosis and disc herniations Management of less common inflammatory and infectious spinal diseases such as spondylarthropathies, osteomyelitis, discitis, and fungal and tubercular infections Oncologic topics including primary, intradural extramedullary, and intramedullary spinal cord tumors and thoracic spine metastases Surgical treatment of pediatric and adult deformities including congenital, idiopathic, and degenerative scoliosis Classification of thoracic spinal fractures, discussion of complete and incomplete thoracic spinal cord injuries, posterior and ventral treatment of thoracic spine fractures, and osteoporotic compression fractures This is an invaluable evaluation and management tool for neurosurgical and orthopaedic residents and practicing spine surgeons who treat patients with common to complex thoracic spinal pathologies. This book includes complimentary access to a digital copy on https://medone.thieme.com.

This book is a comprehensive textbook of primary and metastatic skeletal system tumours which provide clinical, pathological and imaging data of the skeletal system tumours appropriate for all clinicians who are practicing in oncology wards, especially orthopaedic surgeons. In this book, we discuss the diagnosis and treatment of skeletal system tumours, their clinical signs, and symptoms and we also discuss their pathological aspects of the tumours. We conclude with important images such as plain radiographs, CT scans, MRIs, and bone scan. The most helpful data of each tumour is brought together in order to help patients and clinicians of this widespread part of medicine.

Die Kinderorthopadie stellt ein zentrales Feld in der Gesamtorthopadie dar, da ein grosser Teil orthopadischer Probleme seine Ursachen in den Wachstumsphasen hat. Kurz und pragnant vermittelt J. Matussek alles Wichtige in Theorie und Praxis zum Thema Kinderorthopadie und -traumatologie: 1 Entwicklung des Bewegungssystems von der Befruchtung bis zum Neugeborenen 2 Kinderorthopadische Untersuchung 3 Erkrankungen der kindlichen Bewegungs- und Halteorgane 4 Infektionen im Wachstumsalter 5 Tumoren im Wachstumsalter 6 Kindertraumatologie Mehr zum Thema "Orthopadie und Unfallchirurgie" findet der Leser in Grifka, Kuster "Orthopadie und Unfallchirurgie". Matusseks "Kinderorthopadie und Kindertraumatologie" wurde aus diesem Titel ausgekoppelt.

Cerebral palsy presents stable encephalopathy that systemically influences on the child's and adult's organism. Orthopedic complications of cerebral palsy possess on the contrary progressive features and those complications cause gradual failure of motor ability of a person: impaired walking, loss of postural ability, reduced self-care and inclusion, finally quality of life becoming much worse. That is why orthopedic aspects are of great importance in children with cerebral palsy. This volume presents a collection of chapters covering a wide range of problems, from a system of universal classification of dysfunctions in Cerebral Palsy and practical issues of prevention of orthopedic complications orthopedic to surgery (diagnostics and quantitative interpretation of gait disorders in such patients, optimal methods of surgical intervention, hip surgery, spinal surgery) and aspects of nutritive status of this specific category of patients, associated comorbidities and their influence and connection with orthopedic problems. Furthermore, three chapters are dedicated to the anesthetic aspects of orthopedic surgery. The substantiation is given to the methods of combined anesthesia and sedation during surgery, as well as in the immediate postoperative period, taking into account concomitant epilepsy, increased intracranial pressure and spasticity in such children. Single-event multilevel orthopedic surgery is a recognized gold standard in ambulatory patients, though it varies according to gait patterns and associated orthopedic problems causing motor disorders. The book contains explanations and methodology of surgeries for conventional gait patterns, as well as in iatrogenic disorders caused by previous unreasonable interventions. The chapter on the correction of deformities and dysfunctions of the upper limb shows the first applied transfer of m.flexor cubitus ulnaris to the radius, which gave extremely positive results both in terms of function and aesthetics. Unfortunately, in Russia the number of CP patients with iatrogenic orthopedic disorders is high. Extremely negative consequences in the form of weakness of the triceps muscles after percutaneous fibromyotomies (so-called "Ulzibat method") or lengthening of the Achilles tendon in diplegia performed before the age of five years and before the development of muscle retraction lead to the development of crouch gait even in patients with high motor potential (GMFCS I, II). This complication of unreasonable surgical interventions develops in 5-7 years after primary surgery and in the opinion of doctors and parents is not related to previous procedures. This book, based on 3D-instrumented gait analysis, shows the features of iatrogenic crouch gait, as well as methods of surgical correction of this difficult situation. The data presented in this book are based, on the one hand, on the personal practical and scientific experience of each author, and on the other hand, the entire team of authors works in collaboration with each other, coordinating their decisions and interventions with colleagues, thus ensuring continuity in treatment of children and adults suffering from cerebral palsy.

Highly Commended, BMA Medical Book Awards 2013 Orthopaedic problems account for over one-third of all medical and surgical problems. Mercer's Textbook of Orthopaedics and Trauma provides all the information required by the senior trainee or qualified specialist to improve understanding and management of any given condition or disease in this area. Since its first edition over 75 years ago, this volume has been considered the definitive orthopaedic text, integrating clinical knowledge of musculoskeletal disorders with the latest basic science research. Now in its tenth edition, the book has been comprehensively revised by a stellar team of international authors. This evidence-based text reflects the knowledge distilled from worldwide literature, clinical experience, basic science research, and various orthopaedic exit examinations. Mercer's Textbook of Orthopaedics and Trauma will be invaluable to trauma and orthopaedic surgeons at all stages of their professional lives. It will also be an indispensable reference for clinicians, rheumatologists, primary care physicians, and many other health professionals who need reliable and up-to-date information on the musculoskeletal system. Print Versions of this book also include access to the ebook version.

Anatomical guide leverages exceptional dissection images to elucidate the biomechanics of the hand and upper extremity The hand is a unique instrument that executes the commands of the brain and expresses the nuances of the mind. The Grasping Hand: Structural and Functional Anatomy of the Hand and Upper Extremity by Amit Gupta and Makoto Tamai is a state-of-the-art book that details the functions of the hand to feel, receive, gather, collect and hold, as well as the complex role that the whole upper extremity plays in enabling these actions. The anatomical structures intrinsic to these functions are detailed through illuminating cadaveric dissections and succinct text. Organized in 5 sections and 38 chapters, the book begins with a chapter detailing the intriguing history of hand anatomy, followed by a section encompassing the structural and functional fundamentals. The third section covers general anatomy and function, with discussions of the nerves and vascularity of the upper extremity, as well as the brachial plexus. The fourth section features 26 anatomically organized chapters from the shoulder to the fingertip with anatomical and functional insights on the joints, fascia and retinacula, interosseus membrane, tendons and more. The single chapter comprising the final section covers imaging and anatomy. Key Highlights Pioneers in modern hand surgery share vast collective knowledge and pearls on hand and upper extremity anatomy and biomechanics Over 1,100 exquisite, original dissections of lightly embalmed fresh cadaveric arms provide unique visual insights about underlying tissues and structures High quality, never before published original photographs enhance understanding of anatomy, physiology, and pathology This practical resource is ideal for reviewing anatomy and biomechanics prior to performing hand, wrist, arm, elbow, and shoulder surgery, making it essential reading for orthopaedic surgeons, fellows, and hand specialists. This book is also useful for students of human anatomy, physical and occupational therapists, medical students, and anyone interested in upper extremity anatomy and function. This book includes complimentary access to a digital copy on https://medone.thieme.com.

Das Standardwerk der Medizintechnik Life Science Engineering erfahrt mit der vorliegenden 5. Auflage weitere wichtige Erganzungen: durch die neuen Kapitel Sportorthopadische Medizintechnik, Blutpraparate, Textilien fur Implantate, Detektion elektrischer Signale aus dem Korper (EKG, EMG, EEG), Single-Use-Instrumente, Plastische und rekonstruktive Mund-Kiefer- und Gesichtschirurgie, Atmospharische Plasmabehandlung von Oberflachen, Neue Erkenntnisse der Huftendoprothetik, Exoprothetik, Neurorehabilitation, Moderne Augenimplantate und Technische Ausstattung im Rettungswesen werden die anwendernahen klinisch orientierten Themen abgerundet.

Die Zertifizierung in den Life Science Gebieten Medizintechnik, Kosmetik, Pharma und Food (Nahrungsmittel) nimmt umfassenden Raum ein und wird erstmals prasentiert. Es wird damit auf Anforderungen der verschiedenen nationalen Gesetzgeber reagiert, die fur die Inverkehrbringung der zugehorigen Produkte gelten.

Als Premiere werden in einem Technologie-Werk zur Medizintechnik mit Erfahrungen aus der Schnittstelle Schule-Hochschule (Ruckwartsintegration der medizintechnischen Lehre) neue didaktische Impulse gesetzt, um sehr fruh Schulern und Lehrkraften der weiterfuhrenden Schulen Einstiege in die faszinierende Welt der Hochtechnologien in Life Sciences zu erleichtern und Berufsaussichten zu eroffnen. Praktische Beispiele und Erfahrungsberichte werden vermittelt.

Der Leser gewinnt umfassenden Einblick in die diagnostische und therapeutische Medizintechnik, in das Life Science Engineering und in die wichtigsten angrenzenden Gebiete. "

Ein erfahrener Fussspezialist beschreibt spezielle operative Eingriffe am Fuss, wie z.B. - Achillessehnenruptur - Arthroskopie des oberen Sprunggelenks - Metatarsophalangealgelenk - Haglundsporn - Ruckfussosteotomien - Behandlung des Pes plano valgus - Vorfusschirurgie - OSG Endoprothetik. Eine OP-Anleitung, die in ihrem systematischen Aufbau und den im Operationssaal erstellten Zeichnungen jeden Eingriff nachvollziehbar macht und Empfehlungen aus erster Hand enthalt. Ein wichtiges Instrument fur alle Unfallchirurgen und operativ tatigen Orthopaden. Ein Arbeitsbuch "aus der Praxis - fur die Praxis".

This book is a comprehensive reference and practical guide on the technology and application of ultrasound to the musculoskeletal system. It is organized into two main sections. The first is devoted to general aspects, while the second provides a systematic overview of the applications of musculoskeletal ultrasound in different areas of the body. Each chapter of the second section provides an introduction on clinical anatomy and the essentials of clinical history and physical examination. Thereafter, performance of the ultrasound study is explained and the normal and pathological anatomy is reviewed. To assist in understanding, the ultrasound scans are correlated with drawings, photographs, images obtained using other modalities, and anatomic specimens. There is a generous complement of high-quality illustrations based on high-end equipment. This book contains a wealth of invaluable information.

The idiopathic inflammatory myopathies (IIM) are a rare group of autoimmune diseases, negatively affecting the lives of an estimated 250,000 people worldwide. Delays in diagnosis often occur owing to a lack of recognition of disease presentation, or misdiagnosis, both of which can lead to muscle atrophy. This new addition to the Oxford Rheumatology Library series focuses on providing a summary of what is currently understood about the epidemiology of myositis, controversies in diagnosis criteria, clinical features, and the current paradigms for treatment and intervention. Designed to bring together the multi-disciplinary involvement of healthcare professionals for IMM patients, this is the first easy-to-navigate guide for the practical management of myositis. This is an essential guide for both physicians and trainees in Rheumatology, Neurology, and Dermatology specialities.

Das patellofemorale Schmerzsyndrom ist eines der haufigsten Knieprobleme korperlich aktiver Personen. Die Knieschmerzen sind oft abhangig von sportlicher Aktivitat. Jugendliche und Erwachsene sind betroffen. Die Kniebeschwerden treten gewohnlich nach einer Kniebelastung auf und konnen durch Reduzierung der sportlichen Aktivitat gebessert werden. Die therapeutischen Moglichkeiten sind vielfaltig und reichen von der konservativen physikalischen und medikamentosen Therapie bishin zu einer grossen Zahl von verschiedenen Operationstechniken. Der gesamte Themenkomplex einschliesslich der sozial-medizinischen Bedeutung des Krankheitsbildes wird von einem internationalen Autorenteam fundiert und praxisnah dargestellt."

Die Huftendoprothetik gehoert zu den wichtigsten Entwicklungen in der Orthopadie. Gerade weil es nicht die Huftendoprothese gibt, die allen Erfordernissen des einzelnen Patienten gerecht wird, ist ein Erfahrungsaustausch und eine Bestandsaufnahme nach z.T. Jahrzehnte langer Erfahrung mit den einzelnen Prothesensystemen wichtig. Die Beitrage im Buch spiegeln den heutigen Stand des Wissens wider, wobei sich der Bogen von der voll zementierten Bogenschaftprothese bis zur computerassistierten Schaftimplantation, von der Freihandimplantation der Pfanne bis zu navigationsgestutzen Pfannenverankerung spannt. Alle Orthopaden und Unfallchirurgen, die Patienten mit Huftendoprothesen betreuen, finden in diesem Buch einen aktuellen UEberblick der gangigen Verankerungsprinzipien und deren mittel- bis langfristigen Ergebnisse - zusammengestellt von Spezialisten aus dem In- und Ausland.

A practical, hands-on manual for surgeons of all levels on the management of foot and ankle trauma. The approaches are presented in a systematic, casebased format, ranging from simple to more complex cases. It provides step-by-step coverage of a wide range of basic to advanced techniques and procedures for the management of fractures, dislocations and soft tissue injuries of the foot and ankle. While a single case can be approached in a variety of ways, this book seeks to provide important guidelines which apply to most situations that may arise in foot and ankle injuries. It will be of value to anyone providing care for foot and ankle injuries. This book focuses on: General considerations in foot and ankle surgery Clinical and radiographic evaluation Decision-making and options for nonoperative treatment Preoperative planning Surgical approaches Avoiding pitfalls Managing risks and complications Alternative techniques Postoperative rehabilitation Key features include: Contributions from 48 surgeons from 14 countries 59 detailed cases covering a comprehensive range of foot and ankle injuries More than 1,650 high-quality illustrations and images

Dauernde Knieinstabilitat durch traumatische ligament are oder meniskale Schaden wie auch die direkte traumatische Sch1idigung der kartilaginaren Oberflache der Gelenke und des subchondra- len Knochens sind wesentliche Faktoren in der Entstehung der sekundaren Arthrose. Eine normale Gelenkfunktion ohne intak- ten Gelenkknorpel ist nicht moglich, was umso erstaunlicher ist, als der menschliche Gelenkknorpel nur wenig Potenz zur Rege- neration besitzt. Da bisher keine wissenschaftlichen Methoden bekannt sind, die den ProzeiS der zunehmenden Knorpeldegene- ration vermeiden konnen, muiS es heute unser Ziel sein, den iso- lierten traumatischen Knorpelschaden moglichst fruhzeitig und effektiv zu behandeln und ein instabiles Knie zu stabilisieren. Ausgelost durch Meldungen in der Presse uber die erfolgreiche Transplantation von autologen Chondrozyten und Chondrozyten- zylindern und die In-vivo-Neubildung von hyalinem Knorpel wurde bei Patienten und ihren Anten viel Hoffnung geweckt. Es scheint, daiS wir an der Schwelle zu einer neuen Ara in der Be- handlung von Knorpelschaden stehen. Wenn auch Langzeitresul- tate der verschiedenen konkurrierenden Verfahren noch nicht zur Verfugung stehen konnen, sind die Resultate bisher vielver- sprechend. Wir sind jedoch noch weit davon entfernt, daiS das Problem des Knorpelschadens und des instabilen Kniegelenkes gelost ware.

Die Entscheidung fur ein kunstliches Kniegelenk fallt Patienten haufig schwer, auch wenn die Wahrscheinlichkeit hoch ist, dass sich ihre Lebensqualitat nach der Operation deutlich verbessert. Der Band hilft Betroffenen, indem er Antworten auf wichtige Fragen liefert: zur Anatomie des Knies, zur Entstehung von Arthrose und zu verschiedenen Prothesentypen. Auch die Vorbereitung auf die Operation, verschiedene Operationsverfahren und die Phase der Rehabilitation werden leicht verstandlich erlautert. Mit zahlreichen Erfahrungsberichten von Patienten."

It may have once been known as Disease of Kings, but gout is a growing problem for ordinary people around the world. This book brings together multinational expertise to draw out an understanding of this disease that will be useful for the academic, the clinician and indeed the sufferer of gout. Highlighting recent understandings of the genetic background to the condition, with detailed pathophysiology and epidemiology, this book brings together and illustrates the disease mechanisms that cause gout. There follows both an academic and practical appraisal of the dietary risk factors for the development of gout, and the cardiovascular associations that heighten morbidity. With state of the art imaging modalities, the process and sequelae of the disease is captured within the human body, describing in pictures the damage and effect that gout crystals can produce. That damage can be avoided however, if simple principles of treatment and lifestyle modifications are followed. Horizon scanning for yet more drugs to address this growing and unmet need is highlighted as new options that have either recently become available or will be accessible in the near future are explored. With the increasing incidence and prevalence of this condition we are all going to have greater exposure to gout. This book is a timely resource, written by experts, yet accessibly written for all, and certainly not just for kings.

The second edition of this practical guide has been fully revised to provide orthopaedic surgeons and trainees with the latest advice and protocols for the management of infection after orthopaedic procedures. Divided into two sections, the first part of the manual covers preparation of the operating theatre and personnel, and sterilisation. The second part of the book discusses preparation of the perioperative patient, intraoperative protocols, postoperative management, and antibiotics. Highly illustrated with clinical photographs and diagrams, this new edition will assist surgeons in the prevention of infection and related complications. Key Points Fully revised, second edition presenting latest advice and protocols for the management of infection after orthopaedic surgical procedures In depth coverage of both operating theatre and personnel preparation, and perioperative patient Includes intraoperative protocols Previous edition (9789351526537) published in 2015

With an increase in the longevity of the global population, care of the functional, cognitive, and physical health of older adults is essential. There has been a dramatic demographic shift toward a growing aging population and an increase in osteoporotic fractures that has occurred over the last few decades especially in Western countries. This clearly demonstrates the need for a comprehensive approach to treating fragility fractures by surgeons, geriatricians, and care staff. Osteoporotic Fracture Care is the first book of its kind to offer a well-rounded and comprehensive resource on fragility fractures and orthogeriatric care designed to help new and experienced surgeons, geriatricians, physicians, and care personnel to better work together and develop interprofessional and interdisciplinary systems so as to treat patients more effectively. The book contains 44 chapters and is divided into three sections: "Principles", "Improving the system of care", and "Fracture management". The book's key features are: In-depth insight into the needs of older adults and how to best improve patient care, patient outcome, and reduce system costs Twenty detailed and illustrative case-based chapters giving the reader a wide array of options to improve patient care and outcomes More than 1,000 high-quality x-rays, clinical images, and illustrations

Musculoskeletal ultrasound has seen a considerable surge in usage in recent years. Its advantages are manifold. Given adequate training of the examiner, it is very cost-effective; there is no ionizing radiation to contend with; the scanners are normally highly portable; and it enables certain interventional procedures to be performed with great accuracy (therapeutic injections of local anesthetics and/or corticosteroids into areas of complex anatomy, e.g., the shoulder). In this book, the anatomic areas are organized in chapter pairs, of which the first part of the pair summarizes the diagnostic imaging of that area from various angles so as to obtain the standard images necessary for reliable evaluation. The second part covers the image-guided injection techniques themselves, including requisite equipment. Key Features: Concise texts accompanied by typical US scans, brilliant anatomic illustrations, and many photographs showing proper scanner placement Juxtaposes normal and pathologic anatomy for maximum understanding Detailed and lucid description of all common injection procedures, appropriately illustrated Resteghini's Diagnostic Musculoskeletal Ultrasound and Guided Injection: A Practical Guide is an essential introductory reference for physical therapists, sports medicine physicians, orthopaedic practitioners new to the method, radiographers, and allied health professionals involved in the diagnosis and therapy of musculoskeletal conditions.

Top Experts Share Clinical Insights on Biological Interventions for Spine-Related Disease Although there have been significant advancements in minimally invasive spinal surgery techniques in the last few decades, optimal outcomes for chronic low back pain remain elusive. A number of promising clinical trials have been conducted using tissue engineering and biological interventions for disc degeneration. Written by renowned innovators, this is the first book that covers implementation of these groundbreaking approaches for disc disease. The text begins with key fundamentals including anatomy and physiology, pathophysiology, imaging and biomechanics to delineate healthy versus diseased spine. Subsequent sections discuss treatment strategies, research findings, and future developments. Throughout each chapter, renowned spine surgeons and scientists share clinical pearls gleaned from hands-on experience. Key Highlights The current state of the art in biological and tissue engineering procedures for spinal disorders Treatment methodologies including nucleus replacement and repair, annulus fibrosus repair, total disc transplantation, and mechanical total disc replacement Innovative treatment strategies for disc regeneration, such as genes and proteins Growth factors including platelet-rich plasma (PRP), which has shown promise for the stimulation and acceleration of bone and soft tissue healing Cell-based therapy for spinal disc regeneration and repair including the use of stem cells and chondrocytes In-depth discussion of research including animal versus human model, in-vitro, and a summary of biologic clinical trials This is a must-have resource for trainee and practicing orthopaedic surgeons and neurosurgeons who treat patients for spine-related conditions. It is essential reading for all clinicians who have an interest in cutting-edge tissue engineering and biological treatment interventions.