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Heat Shock Proteins and the Cardiovascular System (Paperback, Softcover reprint of the original 1st ed. 1997)
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Heat Shock Proteins and the Cardiovascular System (Paperback, Softcover reprint of the original 1st ed. 1997)
Series: Developments in Cardiovascular Medicine, 192
Expected to ship within 10 - 15 working days
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Heat shock proteins (HSP) were originally described in heat-shocked
drosophila by Ritossa in the early 1960's. In the last 5 years it
has become apparent that these heat shock proteins have important
functions both in the normal cell and in the stressed cell. These
proteins constitute an endogenous protective system; mutations in
the heat shock proteins can be lethal, and there are no known
organisms without heat shock proteins. The first observations on
heat shock proteins and the heart were made in the 1980's and
interest in these proteins increased over the decade. In the last
few years there has been an exponential growth in number of papers
published on heat shock proteins and the heart. Heat shock proteins
have been implicated in a number of cardiovascular research areas
including ischemia, hypertrophy, aging, and atherosclerosis, and
this list is growmg. The purpose of this volume is to give an
overview of our current understanding of the heat shock proteins in
the cardiovascular system, and to summarize the approaches to the
study of heat shock proteins in the heart. This volume assembles
results from a number of different cardiovascular fields. and
provides a comprehensive review of heat shock proteins in the
cardiovascular system.
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