Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology
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Systemic Treatment of Prostate Cancer (Paperback)
Loot Price: R359
Discovery Miles 3 590
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Systemic Treatment of Prostate Cancer (Paperback)
Series: Oxford Oncology Library
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Loot Price R359
Discovery Miles 3 590
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Prostate cancer is one of the commonest cancers in men in the
western world, and the prevalence is rising currently due to
improvements in screening and treatment. Serum PSA represents a
useful marker of disease. It has frequently a long natural history,
creating the opportunities for multiple sequential therapeutic
interventions. For patients with high risk local disease or with
metastases, endocrine therapy is central to management. Hormone
ablation has long been the mainstay of endocrine therapy in this
group of patients, though anti-androgens, oestrogens, and
corticosteroids can also cause remissions. In recent years
effective and well-tolerated chemotherapy regimens have been
developed and evaluated. Docetaxel has an established role, and a
range of biologically-targeted agents are in development.
The dominant pattern of metastatic spread is to the axial skeleton
and most symptomatic care is directed to palliation of bone pain.
The role of bisphosphonates remains controversial, but
bone-directed isotopes such as Strontium-89 are effective.
Part of the Oxford Oncology Library, this pocketbook summarizes the
up-to-date information on the use of systemic therapies in the
management of prostate cancer (early stage, metastatic disease, and
treatment of "biochemical" recurrence). With contributions from
leading oncologists from both Europe and the USA, the book provides
a practical guide to the range of endocrine and cytotoxic therapies
currently available to clinicians, as well as to other palliative
anticancer strategies, and will be valuable to all health
professionals involved in the management of patients with prostate
cancer.
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