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Mitochondrial Dysfunction in Neurodegenerative Disorders (Hardcover, 2nd ed. 2016)
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Mitochondrial Dysfunction in Neurodegenerative Disorders (Hardcover, 2nd ed. 2016)
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This second edition brings together up-to-date contributions from
leaders in the field internationally on the various ways in which
mitochondrial dysfunction contributes to the pathogenesis of
neurodegenerative diseases, including Parkinson's disease,
Alzheimer's disease and multiple sclerosis. The reader is guided
through the basic functions of mitochondria and the mechanisms that
lead to their dysfunction, and on to the consequences of this
dysfunction for neuronal function before finishing with the
modelling of these disorders and discussion of new potential
therapeutic targets. Additional chapters have been added to the
book to reflect advances in the field and there are many new
contributors and topics, including how mitochondria are degraded
and the interaction of the mitochondria with pathologically
relevant proteins. Mitochondrial Dysfunction in Neurodegenerative
Disorders provides an accessible, authoritative guide to this
important area for neurologists; research and clinical
neuroscientists; neuropathologists; and residents with an interest
in clinical research.
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