Respiratory failure is a complex disease process whereby the
underlying disease and therapeutic measures interact. This book
contains an extensive bibliographic review, focusing on preventive
and therapeutic studies, that was methodologically standardized,
with authors assessing and classifying studies according to
statutes of evidence-based medicine. It considers the epidemiology
and outcome of mechanical ventilation; addresses ventilator modes
and utility of pulmonary mechanics monitoring for treatment;
analyzes physiologic effect and patient-outcomes of pulmonary
recruitment and lung protective ventilation procedures; describes
complications that can be present in these patients such as
ventilator-associated pneumonia and useful methods to prevent
respiratory infections; covers the impact of bronchodilators,
corticosteroids, and antibiotics in acute exacerbation of chronic
obstructive pulmonary disease; discusses how, when, and in whom to
do tracheostomy; and evaluates the use of sedation and
neuromuscular blockade as well as current clinical trials in acute
lung injury.
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