Crystallization is an important technique for separation and
purification of substances as well as for product design in
chemical, pharmaceutical and biotechnological process industries.
This ready reference and handbook draws on research work and
industrial practice of a large group of experts in the various
areas of industrial crystallization processes, capturing the
essence of current trends, the markets, design tools and
technologies in this key field. Along the way, it outlines trouble
free production, provides laboratory controls, analyses case
studies and discusses new challenges.First the instrumentation and
techniques used to measure the crystal size distribution, the
nucleation and solubility points, and the chemical composition of
the solid and liquid phase are outlined. Then the main techniques
adopted to control industrial crystallizers, starting from
fundamental approaches to the most advanced ones, including the
multivariable predictive control are described. An overview of the
main crystallizer types is given with details of the main control
schemes adopted in industry as well as the more suitable sensors
and actuators.
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