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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology
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Nevogenesis - Mechanisms and Clinical Implications of Nevus Development (Hardcover, 2012)
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Nevogenesis - Mechanisms and Clinical Implications of Nevus Development (Hardcover, 2012)
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The "Abtropfung" theory that nevi develop through the migration of
nevus cells from the epidermis to the dermis prevailed for almost a
century until the "Hochsteigerung" theory postulated the reverse
pattern of migration. Most recently, however, new insights gained
from epidemiology, cross-sectional and longitudinal studies of
nevi, dermoscopy and confocal microscopy, and cellular and
molecular studies have brought into question both of these
theories. This book provides a comprehensive guide to current
knowledge about nevogenesis by presenting these latest advances and
in addition discusses issues yet to be resolved. It will assist
practicing physicians in effectively managing patients with a
variety of nevi and will also be of great value to researchers in
the field. Importantly, since nevi are associated with an increased
risk of melanoma, understanding nevogenesis may help to unravel
some of the mysteries of melanomagenesis.
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