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Books > Medicine > Other branches of medicine > Pharmacology
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Ethnopharmacology of Medicinal Plants - Asia and the Pacific (Paperback, Softcover reprint of hardcover 1st ed. 2007)
Loot Price: R5,586
Discovery Miles 55 860
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Ethnopharmacology of Medicinal Plants - Asia and the Pacific (Paperback, Softcover reprint of hardcover 1st ed. 2007)
Expected to ship within 10 - 15 working days
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In 1860, Oliver Wendell Holmes pointedly expressed himself to the
Massachusetts Medical Society: "I firmly believe that if the whole
Material Medica, as now used, could be sunk to the bottom of the
sea, it would be all the better for mankind, and all the worst for
the fishes." Should one think the same about the current approach
in drug discovery from plants? Probably yes. Despite the spending
of billions of US dollars, and three decades of efforts,
high-throughput screenings have only allowed the discovery of a
couple of drugs. One could have reasonably expected the discovery
of an arsenal of drugs from the millions of plant extracts randomly
tested, but "hits" can be inactive in vitro or too toxic, some
molecules need to be metabolized first to be active, and
false-positive and false-negative results are common. The bitter
truth is that the robotic approach in discovering drugs from plants
has proven, to date, its inability to excavate the hundreds of
molecules that will contribute to the health progress of Man.
However, one can reasonably see that the last patches of primary
rainforest on earth hold still hundreds of spectacularly active
drugs that await discovery.
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