The genomic approach of technology development and large-scale
generation of community resource data sets has introduced an
important new dimension in biological and biomedical research.
Interwoven advances in genetics, comparative genomics, high
throughput biochemistry and bioinformatics are combining to attack
basic understanding of human life and disease and to develop
strategies to combat disease. Genomic Research began with The Human
Genome Project (HGP), the international research effort that
determined the DNA sequence of the entire human genome, completed
in April 2003. The HGP also included efforts to characterise and
sequence the entire genomes of several other organisms, many of
which are used extensively in biological research. Identification
of the sequence or function of genes in a model organism is an
important approach to finding and elucidating the function of human
genes. Integral to the HGP are similar efforts to understand the
genomes of various organisms commonly used in biomedical research,
such as mice, fruit flies and roundworms. Such organisms are called
"model organisms," because they can often serve as research models
for how the human organism behaves. This book brings together
leading research from throughout the world in this cutting-edge
field.
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