Pooling designs have been widely used in various aspects of DNA
sequencing. In biological applications, the well-studied
mathematical problem called ?group testing? shifts its focus to
nonadaptive algorithms while the focus of traditional group testing
is on sequential algorithms. Biological applications also bring
forth new models not previously considered, such as the
error-tolerant model, the complex model, and the inhibitor model.
This book is the first attempt to collect all the significant
research on pooling designs in one convenient place. The coverage
includes many real biological applications such as clone library
screening, contig sequencing, exon boundary finding and
protein?protein interaction detecting and introduces the
mathematics behind it.
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