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Mass Spectrometry in Biotechnological Process Analysis and Control (Paperback, Softcover reprint of the original 1st ed. 1987)
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Mass Spectrometry in Biotechnological Process Analysis and Control (Paperback, Softcover reprint of the original 1st ed. 1987)
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This book is based on the contributions to the IFAC-Workshop "Mass
Spectro metry in Biotechnological Process Analysis and Control"
held in Graz, Austria from 23 to 24 October 1986. The idea to
organize this workshop and further to prepare these proceedings was
stimulated by the following facts. Biotechnological processes
urgently need better on-line instrumentation. Mass spectrometry
(MS) offers a great potential to especially analyse gases and
volatile compounds. It is, however, considered that this potential
by far is not exhausted. The main reason for this is that MS often
still is considered to be a very expensive technique requiring the
permanent attention of a MS expert. In addition methods have not
yet been developed to a user friendly state. On-line MS-methods are
available to a certain extent, but need further development. To
stimulate such development an interdisciplinary effort is
necessary. Needs of industrial and university users and experience
of physicists and instrument manufacturers have to be brought into
a hopefully fruitful discussion. An introductory article describes
the bioprocess background including a brief summary of the state of
the art in bioprocess sensor and parameter estimation development,
and the potential MS offers for bioprocess monitoring. In the first
chapter on "Instrumentation and Gas Analysis" a general overview on
some developments in MS-instrumentation is given initially by
Schmid. Then the presently available instrumentation for bioprocess
monitoring is discussed by instrument manufacturers (Winter;
Schaefer and Schultis; Bartman)."
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