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Modelling Optimization and Control of Biomedical Systems (Hardcover)
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Modelling Optimization and Control of Biomedical Systems (Hardcover)
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Shows the newest developments in the field of multi-parametric
model predictive control and optimization and their application for
drug delivery systems This book is based on the Modelling, Control
and Optimization of Biomedical Systems (MOBILE) project, which was
created to derive intelligent computer model-based systems for
optimization of biomedical drug delivery systems in the cases of
diabetes, anaesthesia, and blood cancer. These systems can ensure
reliable and fast calculation of the optimal drug dosage without
the need for an online computer--while taking into account the
specifics and constraints of the patient model, flexibility to
adapt to changing patient characteristics and incorporation of the
physician's performance criteria, and maintaining the safety of the
patients. Modelling Optimization and Control of Biomedical Systems
covers: mathematical modelling of drug delivery systems; model
analysis, parameter estimation, and approximation; optimization and
control; sensitivity analysis & model reduction;
multi-parametric programming and model predictive control;
estimation techniques; physiologically-based patient model; control
design for volatile anaesthesia; multiparametric model based
approach to intravenous anaesthesia; hybrid model predictive
control strategies; Type I Diabetes Mellitus; in vitro and in
silico block of the integrated platform for the study of leukaemia;
chemotherapy treatment as a process systems application; and more.
Introduces readers to the Modelling, Control and Optimization of
Biomedical Systems (MOBILE) project Presents in detail the
theoretical background, computational tools, and methods that are
used in all the different biomedical systems Teaches the theory for
multi-parametric mixed-integer programming and explicit optimal
control of volatile anaesthesia Provides an overview of the
framework for modelling, optimization, and control of biomedical
systems This book will appeal to students, researchers, and
scientists working on the modelling, control, and optimization of
biomedical systems and to those involved in cancer treatment,
anaesthsia, and drug delivery systems.
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