Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Genetics (non-medical) > DNA
|
Buy Now
DNA Adducts - Formation, Detection & Mutagenesis (Hardcover)
Loot Price: R4,526
Discovery Miles 45 260
|
|
DNA Adducts - Formation, Detection & Mutagenesis (Hardcover)
Expected to ship within 12 - 17 working days
|
Numerous physical and chemical stress factors, endogenous or
exogenous, challenge living organisms. Metabolisation processes
generate highly reactive intermediates which can covalently bind to
DNA, resulting in bulky addition products called "adducts." DNA
adduct formation appears to be a general response of plants to
organic chemical exposure, whether in controlled conditions or in
the field. In particular, common carcinogenic pollutants and
pesticides promote the formation of DNA adducts in plants. The
authors of this book examine the development of DNA adducts, as
well as the ways in which they can be eliminated due to DNA repair
pathways. In this book, the data from in vivo transgenic assays is
also examined, which can help to clarify specific pre-mutagenic
adducts, DNA repair functions and mutational events that may be
involved in the mutagenicity of human carcinogens. Other chapters
in this book identify and discuss novel anthracyclines capable of
forming DNA adducts, the role of DNA adducts as early biomarkers in
the screening and development of marine anticancer drugs, the
genotoxicity, such as DNA adduct formation, of air pollutants and
its assessment by in vivo mutagenesis and a discussion of oxidative
DNA damage, which can play an important role in the carcinogenic
processes of PAHs and aromatic amines, in addition to bulky-DNA
adducts formation.
General
Is the information for this product incomplete, wrong or inappropriate?
Let us know about it.
Does this product have an incorrect or missing image?
Send us a new image.
Is this product missing categories?
Add more categories.
Review This Product
No reviews yet - be the first to create one!
|
|
Email address subscribed successfully.
A activation email has been sent to you.
Please click the link in that email to activate your subscription.