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Clinical Experiences with Budipine in Parkinson Therapy (Paperback)
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Clinical Experiences with Budipine in Parkinson Therapy (Paperback)
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Some 20 years ago the introduction of levodopa opened a new era in
the treatment of Parkinson's disease. Although levodopa remains the
single most effective drug for the treatment of this maladie,
challeng- ing therapeutic problems arise in many patients after
several years of sustained treatment. Among these, fluctuations in
motor performance and drug-induced involuntary movements are the
most troublesome. The search for improved antiparkinsonian
medications therefore con- tinues and important new developments
have already occurred, for example the introduction of the
dopaminergic ergots and the selective MAO-B-inhibitor selegeline
(deprenyl) into routine treatment. The International Workshop on
Parkinson's Disease held in Inns- bruckjIgls primarily considered a
new compound with antiparkinsonian properties unrelated to any of
the conventional drugs - the diphenyl- ex- piperidine compound
budipine. The present volume records the perimental and clinical
data on budipine presented at the meeting. The editors felt
especially encouraged by the authorative biochemical,
physiological, clinical and therapeutic reviews that were given at
this symposium by outstanding experts in the field of
extrapyramidal dis- orders. Their inclusion should make this volume
a valuable source of information on a variety of current research
aspects into Parkinson's disease. InnsbruckjLondon, October 1984
The Editors v Contents James Parkinson and the Treatment of His
Disease. G. Stern ...
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