This book is an excellent introductory text describing the use of
bioinformatics to analyze genomic and post-genomic data. It has
been translated from the original popular French edition, which was
based on a course taught at the well-respected Ecole Polytechnique
in Palaiseau. This edition has been fully revised and updated by
the authors.
After a brief introduction to gene structure and sequence
determination, it describes the techniques used to identify genes,
their protein-coding sequences and regulatory regions. The book
discusses the methodology of comparative genomics, using
information from different organisms to deduce information about
unknown sequences. There is a comprehensive chapter on structure
prediction, covering both RNA and protein. Finally, the book
describes the complex networks of RNA and protein that exist within
the cell and their interactions, ending with a discussion of the
simulation approaches that can be used to model these networks.
Praise from the reviews:
""In context of the new developments the genomic era has
brought, Bioinformatics: Genomics and Post-Genomics becomes a
fundamental and indispensable resource for undergraduate and early
graduate students...insightfully authored...will immensely help
students...in establishing important foundations while shaping
their careers."" NEWSLETTER, BRITISH SOCIETY OF CELL BIOLOGY
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