Recent years have seen a considerable emphasis on growth factors
and the elucidation of their mode of function, which has led to the
recognition that growth factors, their receptors as well as
downstream elements of signalling associated with their function
might be potential targets in therapeutic management of human
diseases. Humanised monoclonal antibodies raised against growth
factor receptors have proved to be valuable for targeted cancer
treatment and in patient management.
This book reviews the latest developments providing insights
into the signalling processes involved in morphogenesis and
pathogenesis with emphasis on using the elements of the signalling
cascades as targets for therapeutic deployment.
Provides afundamental understanding of the basic functions of
growth factors and their receptors, describing how they are linked
in biological processes
Aids the development of therapeutic treatments for cancer
Focuses on the interrelationships and convergence of growth
factors and their receptors in development and pathogenesis and
encourages greater cooperation and integration in the areas of
developmental, cancer and cancer therapeutic research "
General
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