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microRNA: Medical Evidence - From Molecular Biology to Clinical Practice (Hardcover, 1st ed. 2015)
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microRNA: Medical Evidence - From Molecular Biology to Clinical Practice (Hardcover, 1st ed. 2015)
Series: Advances in Experimental Medicine and Biology, 888
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This volume explores microRNA function in a wide array of human
disorders, providing a clinical basis for precision medicine and
personalized therapies using these molecules. The twenty-one
chapters, all authored by internationally-renowned experts, open
with an introduction contextualizing microRNA manipulation within
today's initiatives towards precision medicine. The following
chapters explore the clinical role of microRNAs in the diagnosis
and treatment of metabolic and cardiovascular disorders, focusing
on mitochondrial fitness, arterial hypertension, cardiovascular
remodeling, cerebrovascular disease, pulmonary hypertension,
diabetic kidney disease, and kidney transplantation. The subsequent
chapters discuss the importance of microRNAs in the wound healing
process and in skin disease, in the pathogenesis of allergy, in
human ovulation, and in infection. The book concludes with chapters
which outline the emerging role of microRNAS in doping and detail
microRNA profiling. microRNA: Medical Evidence is an ideal
companion to both microRNA: Basic Scienceand microRNA: Cancer.
Taken together, these three books provide a state-of-the-art
overview of this rapidly-expanding and fascinating field, from
themolecular level to clinical practice. It will be invaluable to
medical students, physicians, and researchers, as a complete and
unique guide in the exploration of microRNA in basic science,
cancer and clinical practice.
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