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The Molecular Basis of Skeletogenesis (Hardcover) Loot Price: R3,088
Discovery Miles 30 880
You Save: R239 (7%)
The Molecular Basis of Skeletogenesis (Hardcover): Gail Cardew, Jamie A Goode

The Molecular Basis of Skeletogenesis (Hardcover)

Gail Cardew, Jamie A Goode

Series: Novartis Foundation Symposia

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List price R3,327 Loot Price R3,088 Discovery Miles 30 880 | Repayment Terms: R287 pm x 12* You Save R239 (7%)

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This book brings together a cross-fertilization of ideas between human molecular genetics, developmental biology, tissue biology and the biochemistry of cell signalling pathways, in order to create new insights into the mechanisms of normal and abnormal skeletogenesis. This broad perspective is essential in order to understand the aetiology of genetic diseases affecting skeletal development at all levels from genotype to phenotype, i.e. from mutation to syndrome.
The book encompasses normal and abnormal skeletogenesis process by process, beginning with the signalling pathways that control early patterning events, then the molecular control of osteoblast, chondrocyte and osteoclast differentiation, joint formation and finally osteoclast activity. Each step takes into consideration the results of mouse gene cloning and knockout studies, human molecular genetics, and new mouse studies stimulated by the human information. Such an integrated approach is essential if this new understanding is to be applied for future therapeutic strategies.

General

Imprint: John Wiley & Sons
Country of origin: United Kingdom
Series: Novartis Foundation Symposia
Release date: 2001
First published: March 2001
Editors: Gail Cardew • Jamie A Goode
Dimensions: 231 x 159 x 20mm (L x W x T)
Format: Hardcover
Pages: 304
ISBN-13: 978-0-471-49433-1
Categories: Books > Medicine > Pre-clinical medicine: basic sciences
Books > Medicine > Surgery
Books > Science & Mathematics > Biology, life sciences
Books > Medicine > Pre-clinical medicine: basic sciences > Anatomy
Books > Medicine > Surgery > Orthopaedics & fractures
Books > Science & Mathematics > Biology, life sciences > Molecular biology
Books > Science & Mathematics > Biology, life sciences > Zoology & animal sciences
Books > Medicine > Pre-clinical medicine: basic sciences > Anatomy > General
Books > Science & Mathematics > Biology, life sciences > Zoology & animal sciences > Animal physiology
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LSN: 0-471-49433-X
Barcode: 9780471494331

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