Reverse Transcriptase Inhibitors in HIV/AIDS Therapy (Paperback, Softcover reprint of hardcover 1st ed. 2006)

A magisterial survey of all aspects of the reverse transcriptase inhibitors (RTIs) used to treat HIV/AIDS, including drug discovery, pharmacology, development of drug resistance, toxicity, and prevention of mother-to-child transmission of HIV/AIDS. The authors synthesize our current understanding of the role of reverse transcriptase in the viral life cycle, describe the discovery and development of eight nucleoside and nucleotide analogs that represent milestones in treatment history, and thoroughly discuss the question of toxicity and resistance to this class of drugs. They also address three non-nucleoside RTIs and their pharmacokinetics and comparative clinical efficacy, new RTIs currently under development, and the impact of approved agents on treatment, in general, and on vertical transmission in the developing world.

General

Imprint:	HumanaPress
Country of origin:	United States
Series:	Infectious Disease
Release date:	November 2010
First published:	2006
Editors:	Gail Skowron • Richard Ogden
Dimensions:	229 x 152 x 30mm (L x W x T)
Format:	Paperback
Pages:	528
Edition:	Softcover reprint of hardcover 1st ed. 2006
ISBN-13:	978-1-61737-695-5
Categories:	Books > Medicine > Clinical & internal medicine > Diseases & disorders > Infectious & contagious diseases > General
LSN:	1-61737-695-7
Barcode:	9781617376955

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