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Coarse-Grained Modeling of Biomolecules (Paperback)
Loot Price: R1,446
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Coarse-Grained Modeling of Biomolecules (Paperback)
Series: Series in Computational Biophysics
Expected to ship within 12 - 17 working days
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"The chapters in this book survey the progress in simulating
biomolecular dynamics.... The images conjured up by this work are
not yet universally loved, but are beginning to bring new insights
into the study of biological structure and function. The future
will decide whether this scientific movement can bring forth its
Picasso or Modigliani." -from the Foreword by Peter G. Wolynes,
Bullard-Welch Foundation Professor of Science, Rice University This
book highlights the state-of-art in coarse-grained modeling of
biomolecules, covering both fundamentals as well as various cutting
edge applications. Coarse-graining of biomolecules is an area of
rapid advances, with numerous new force fields having appeared
recently and significant progress made in developing a systematic
theory of coarse-graining. The contents start with first
fundamental principles based on physics, then survey specific
state-of-art coarse-grained force fields of proteins and nucleic
acids, and provide examples of exciting biological problems that
are at large scale, and hence, only amenable to coarse-grained
modeling. Introduces coarse-grained models of proteins and nucleic
acids. Showcases applications such as genome packaging in nuclei
and understanding ribosome dynamics Gives the physical foundations
of coarse-graining Demonstrates use of models for large-scale
assemblies in modern studies Garegin A. Papoian is the first Monroe
Martin Associate Professor with appointments in the Department of
Chemistry and Biochemistry and the Institute for Physical Science
and Technology at the University of Maryland.
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