A comprehensive, authoritative look at an emergent area in
post-genomic science, Evolutionary genomics is an up-and-coming,
complex field that attempts to explain the biocomplexity of the
living world. "Evolutionary Genomics and Systems Biology" is the
first full-length book to blend established and emerging concepts
in bioinformatics, evolution, genomics, and structural biology,
with the integrative views of network and systems biology.
Three key aspects of evolutionary genomics and systems biology
are covered in clear detail: the study of genomic history, i.e.,
understanding organismal evolution at the genomic level; the study
of macromolecular complements, which encompasses the evolution of
the protein and RNA machinery that propels life; and the
evolutionary and dynamic study of wiring diagrams--macromolecular
components in interaction--in the context of genomic complements.
The book also features: A solid, comprehensive treatment of
phylogenomics, the evolution of genomes, and the evolution of
biological networks, within the framework of systems biologyA
special section on RNA biology--translation, evolution of
structure, and micro RNA and regulation of gene expressionChapters
on the mapping of genotypes to phenotypes, the role of information
in biology, protein architecture and biological function,
chromosomal rearrangements, and biological networks and
diseaseContributions by leading authorities on each topic
"Evolutionary Genomics and Systems Biology" is an ideal book for
students and professionals in genomics, bioinformatics, evolution,
structural biology, complexity, origins of life, systematic
biology, and organismal diversity, as well as those individuals
interested in aspects of biological sciences as they interface with
chemistry, physics, and computer science and engineering.
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