The writing of this monograph was stimulated on the one hand by
experience gained in the study of "cancer families," and on the
other, by the frequent perplexed and bewildered comments made by
numerous physicians who have expressed amaze ment that we could
think that "cancer is hereditary." In reviewing the world
literature it became immediately apparent that no compendium on the
subject of cancer genetics was available to the physician or
research scientist. Therefore this monograph has been written for
the following reasons: 1) To illuminate the problem for those who
may have missed or ignored the evidence supporting a genetic
etiology for certain malignant neoplasms; 2) to supply useful
information to all practicing physicians regarding genetic risks to
their patients; and 3) to provide new thoughts on the subject for
use by cancer investigators. Finally, our paramount hope is that
information gleaned through the reading of this monograph may
contribute to the early dia gnosis of cancer in members of high
risk "cancer families.""
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