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Biomarkers in Cancer Therapy - Liquid Biopsy Comes of Age (Hardcover, 1st ed. 2019)
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Biomarkers in Cancer Therapy - Liquid Biopsy Comes of Age (Hardcover, 1st ed. 2019)
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This book sheds new light on research into liquid biopsy biomarkers
for cancer screening. The chapters in the first half address
exosomes, circulating cell-free DNA and autoantibodies, and main
solid cancers, along with companion biomarkers - all of which serve
as the basis for exploring key research questions for future
clinical trials in the book's second half. The study of biomarkers
has evolved rapidly thanks to advances in precision medicine. While
conventional cancer biomarker research is focused on proteomics or
gene analysis of resected tissue, diagnostic markers have since
become significant in terms of gauging the effectiveness of
molecularly targeted drugs or the likelihood of a favorable
prognosis. In addition, conventional treatment strategy, which
draws on archives of resected tissue samples, is now gradually
being replaced by monitoring with the use of liquid biopsy, which
is poised to become the new mainstream in molecular targeting
therapy. The contributing authors discuss in detail biomarkers,
molecular targets for treatment, monitoring markers to evaluate
treatment responses, prognostic markers, and screening and early
diagnosis. Accordingly, this excellent collection of texts will
benefit not only oncologists, but also medical and biological
researchers and pharmaceutical scientists involved in the latest
cancer research.
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