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Frontiers in Ovarian Cancer Science (Hardcover, 1st ed. 2017)
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Frontiers in Ovarian Cancer Science (Hardcover, 1st ed. 2017)
Series: Comprehensive Gynecology and Obstetrics
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This volume presents the latest advances and the current status of
our understanding regarding ovarian cancer, addressing both the
basic and clinical aspects of the disease. In terms of basic
medicine, the WHO Classification of Tumors of Female Reproductive
Organs was revised in 2014, and that version addresses several new
concepts and histopathological classifications not previously
included. One of the most revolutionary breakthroughs concerns the
genesis of epithelial ovarian tumors, shifting the focus from the
ovarian surface epithelium to serous tubal intraepithelial
carcinomas. Clinically, the mortality rate of epithelial ovarian
cancer has gradually increased over the past few decades, making it
essential to pursue multidisciplinary treatment and apply novel
techniques such as neoadjuvant chemotherapy in daily clinical
practice. The primary clinical task is the effective treatment of
recurrent ovarian cancer with early palliative medicine.
Fertility-sparing surgery may also be pursued depending on
histologic subtypes, stage, extent of disease, and preexisting
ovarian reserve with the concept of oncofertility. On the basis of
the considerations described above, each expert author elucidates
the science of ovarian cancer in detail, thus providing a
collection that will benefit young medical oncologists and seasoned
gynecologists and obstetricians alike.
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