Books > Medicine > Clinical & internal medicine > Paediatric medicine
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The Optimization of Drug Prescribing in Children (Paperback)
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The Optimization of Drug Prescribing in Children (Paperback)
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Total price: R4,314
Discovery Miles: 43 140
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Pediatrics is the form of medical care that is concerned with
children from birth to adolescence, specializing in a variety of
characteristics and changes subjective to each patient.
Undoubtedly, these changes influence drug distribution and
response. The body composition and the processes of biological and
physiological maturation constitute important variables worthy of
consideration in the effort to adequately satisfy the therapeutic
necessities of all the age groups, since different formulations are
required to achieve optimum therapy. The technological advances in
the last decades have endowed humanity with the facilities to
painstakingly analyze biological samples and thus give way to
potential progress in pharmacokinetics and pharmacodynamics. From
this knowledge, it becomes clear that the body is a dynamic model
and thus, brings to light the necessity to individualize treatment
regimens based on parameters of each and every individual, which in
the past was not as important. There are instruments that
contribute to optimizing drug management and safety in the
pediatric population as recommended by the World Health
Organization that rotate on the application of drug monitoring
strategies that would contribute to ensuring the safety of patients
and improve treatment schemes with increasingly safe and effective
drugs. Furthermore, recourses to the therapeutic monitoring of
drugs would become available where a monitoring based principally
on the drug plasma levels is carried out in order to make the
pertinent dose adjustments. The need for this will arise, since the
most effective therapeutic range of many drugs is still unknown;
unnecessarily high concentrations with potential risks of producing
toxicity in patients is something that must be avoided. With these
factors in mind, the decision to compose this book for pediatric
doctors as well as specialists in the health sector who are
dedicated to childcare became apparent, with the hope of portraying
an array of pharmacokinetic knowledge, based on new therapeutic
strategies ensuing from information furnished by research. The
authors are convinced that the consideration of these concepts
would definitely permit the elaboration of optimum and specific
treatment for each pediatric patients.
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