Functional genomics--the deconstruction of the genome to
determine the biological function of genes and gene
interactions--is one of the most fruitful new areas of biology. The
growing use of DNA microarrays allows researchers to assess the
expression of tens of thousands of genes at a time. This
quantitative change has led to qualitative progress in our ability
to understand regulatory processes at the cellular level.This book
provides a systematic introduction to the use of DNA microarrays as
an investigative tool for functional genomics. The presentation is
appropriate for readers from biology or bioinformatics. After
presenting a framework for the design of microarray-driven
functional genomics experiments, the book discusses the foundations
for analyzing microarray data sets, genomic data-mining, the
creation of standardized nomenclature and data models, clinical
applications of functional genomics research, and the future of
functional genomics.
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