Matrix metalloproteases (MMPs) include a group of enzymes important
in the degradation of components of the extracellular matrix (ECM)
and are thought to be universally related to pathology. This book
examines the relationship between matrix metalloproteinases (MMPs)
and oral pathologies, including oral squamous cell carcinoma and
separately, atherosclerosis. The molecular mechanisms regarding
MMPs activation and the use of MMP inhibitors as an effective
treatment in animal models of hypertension are reviewed. The status
of MMPs and their regulators with infectious diseases of bacterial
and protozoan origin that invade host through mucosal surfaces are
explored. Finally, a clinical point of view is provided for the
association between MMPs and bowel diseases.
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