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Bioactive Ceramides in Health and Disease - Intertwined Roles of Enigmatic Lipids (Hardcover, 1st ed. 2019)
Loot Price: R2,933
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Bioactive Ceramides in Health and Disease - Intertwined Roles of Enigmatic Lipids (Hardcover, 1st ed. 2019)
Series: Advances in Experimental Medicine and Biology, 1159
Expected to ship within 10 - 15 working days
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This book is about the various roles of bioactive ceramides and
other sphingolipids in cellular biology. The enigmatic biophysical
and biochemical properties of ceramides and their propensity to
influence membranes whether as rafts or protein-permeable channels
are heavily discussed. Metabolism of ceramides and their
metabolites is also focused with ceramide synthase family of
proteins being a target of extensive review. Ceramide 1-phosphate
and other sphingolipids are also presented in cellular physiology
and pathophysiology. Prokaryotic origins of mitochondria at the
level of membranes and the occurrence of apoptosis in bacteria are
presented. Many aspects of ceramide and sphingolipid biology are
addressed in this book. Its focus is the metabolism of ceramide in
normal and diseased states and the biophysical and biochemical
mechanisms governing the bioactivity of these molecules.
Sphingolipid research has surged over the past thirty years and
this book gathers the recent findings of various aspects of
sphingolipid biochemistry. World-renowned scientists from the field
of lipid biology, specifically sphingolipid biochemistry, were
gathered to write this book. Scholars from most continents of the
globe committed to write diligently about their expertise and the
newest findings in the relevant fields. This book came to fruition
after almost a year and a half of laborious preparation and
diligent writings. This book is targeted to the experienced reader
who is looking to read about the various aspects of bioactive
ceramide signaling, as well as to the newcomer into the field, as
the topics are explained in concise yet very informative manner.
The authors and editor wish all readers a pleasant time reading
this volume, and are adamant that this book will meet all
expectations.
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