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Calcium Entry Pathways in Non-excitable Cells (Hardcover, 1st ed. 2016) Loot Price: R5,707
Discovery Miles 57 070
Calcium Entry Pathways in Non-excitable Cells (Hardcover, 1st ed. 2016): Juan A. Rosado

Calcium Entry Pathways in Non-excitable Cells (Hardcover, 1st ed. 2016)

Juan A. Rosado

Series: Advances in Experimental Medicine and Biology, 898

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Loot Price R5,707 Discovery Miles 57 070 | Repayment Terms: R535 pm x 12*

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Calcium entry pathways in non-excitable cells presents a concise synthesis of thoughtfully selected topics covering from the different calcium entry mechanisms in non-excitable cells to the cellular microdomains and organelles regulating the calcium entry process. Particular attention is given to the fascinating group of ion channels involved in different calcium entry pathways as well as the emerging role of these channels in human disease. Calcium entry is an essential mechanism for cellular function in non-excitable cells. In general, two main calcium entry pathways exist in non-excitable cells: one pathway, named store-operated calcium entry (SOCE) requires store depletion and the second pathway is regulated by receptor occupation, but independently on calcium store depletion. The search for the molecular components of calcium entry has identified the stromal interaction molecule 1 (STIM1), as the calcium sensor of the intracellular calcium stores, and Orai as well as TRP channels as the calcium-permeable channels located in the plasma membrane. The location, interactions and function of these channels are finely regulated by a number of scaffolding proteins, membrane microdomains and cellular organelles that fine tune the amount of calcium entering the cell. Cutting-edge and user-friendly, this volume presents relevant background information, critical analysis of the current observations and directions for future research. The book is intended for basic scientists specializing in cellular biology or ion transport, as well as for biomedical researchers.

General

Imprint: Springer International Publishing AG
Country of origin: Switzerland
Series: Advances in Experimental Medicine and Biology, 898
Release date: May 2016
First published: 2016
Editors: Juan A. Rosado
Dimensions: 235 x 155 x 30mm (L x W x T)
Format: Hardcover
Pages: 471
Edition: 1st ed. 2016
ISBN-13: 978-3-319-26972-6
Categories: Books > Medicine > Pre-clinical medicine: basic sciences > Physiology > General
Books > Science & Mathematics > Biology, life sciences > Cellular biology > General
LSN: 3-319-26972-0
Barcode: 9783319269726

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