Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology
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Molecular Diagnostics in Cancer Patients (Hardcover, 1st ed. 2019)
Loot Price: R4,021
Discovery Miles 40 210
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Molecular Diagnostics in Cancer Patients (Hardcover, 1st ed. 2019)
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This book aims to bring together a broad variety of examples of the
role of pharmacogenomics in current drug development, uncovering
dynamic concentration-dependent drug responses on biological
systems to understand pharmacodynamics responses in human cancer
where genetic lesions serve as tumor markers and provide a basis
for cancer diagnosis. The book describes methods and protocols
applied in molecular diagnostics. It offers pathologists and
researchers providing molecular diagnostic services an array of the
most recent and readily accessible reference to compare methods and
techniques. Highlights include the molecular diagnosis of genetic
aberrations by quantitative polymerase reaction (qPCR),
sequence-specific oligonucleotide arrays, next-generation
sequencing (NGS), CGH arrays-and methodologies directed at the
detection of epigenetic events, high-throughput nucleic acid and
protein arrays, direct sequencing and FISH-based methodologies,
currently used in the diagnosis of solid tumors. The book also
includes an innovative line of treatment in relation to the
molecular prognosis, diagnosis and pharmacogenomics in the actual
practice of clinical findings at molecular levels. The book covers
the applications of numerous genetic testing methodologies; in
approximately the chronological order of discovery and
high-throughput diagnosis using advanced genomic approaches to
identify such genes, in the search for novel drug targets and/or
key determinants of drug reactions. It also promotes a wider
understanding of molecular diagnostics among physicians, medical
students, and scientists in academics, industry and corporate
world.
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