This book provides a comprehensive overview of the biological basis
of renal tumors in childhood and the clinical approaches to their
treatment. Recent advances in our understanding of the molecular
genetics of Wilms and other renal tumors are placed in their
clinical context, including the differing treatment approaches of
immediate surgery or pre-operative chemotherapy. The challenges in
applying this knowledge to improve risk stratification and to
incorporate biologically targeted agents into front-line therapy
are discussed. All of the authors are experts from Europe and North
America and the book has been written specifically as an easy
reference for the practising clinician and the research scientist.
It lays the basis for understanding the future direction of
clinical and translational research to improve outcomes in patients
with childhood renal tumors and will prove indispensable for those
treating or researching into these diseases.
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