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Cardiovascular Genomics - Methods and Protocols (Hardcover, 2009 ed.)
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Cardiovascular Genomics - Methods and Protocols (Hardcover, 2009 ed.)
Series: Methods in Molecular Biology, 573
Expected to ship within 9 - 15 working days
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As two of the leading causes of death worldwide, heart disease and
stroke represent a clear target for genomic research aimed at
deciphering the genes and cellular pathways that underlie
cardiovascular disease and creating improved therapies. In
Cardiovascular Genomics: Methods and Protocols, experts in the
field provide methods for cardiovascular phenotyping of rodent
models in the first section of the volume and for statistical and
bioinformatic integration of phenotype data with genome-wide
genotype and expression data in the second section. Understanding
these diverse methods will allow an individual laboratory to
utilize these genomic methods independently or to better prepare
for collaboration with scientists having expertise in other
disciplines in order to uncover genes affecting cardiovascular
disease. Written in the highly successful Methods in Molecular
Biology (TM) series format, chapters include introductions to their
respective topics, lists of the necessary equipment, materials, and
reagents, step-by-step, readily reproducible laboratory protocols,
and notes on troubleshooting and avoiding known pitfalls.
Cutting-edge and easy-to-use, Cardiovascular Genomics: Methods and
Protocols will enable researchers to identify causal genes and
novel molecular targets that can lead to vital new treatments for
cardiovascular disease.
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