Zygotic Genome Activation - Methods and Protocols (Paperback, Softcover reprint of the original 1st ed. 2017)

This volume provides an overview of zygotic genome activation (ZGA) and the use of recent tools to elucidate the events that occur during ZGA. The chapters in this book cover topics such as: clearance of maternal RNAs, detection of miRNA in mammalian oocytes and embryos, RNA FISH to study ZGA in early mouse embryos, and CRISPR/Cas9-mediated gene targeting during embryogenesis in the mouse and pig. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Thorough and cutting-edge, Zygotic Genome Activation: Methods and Protocols is a valuable resource for scientists and researchers who are interested in learning more about practical approaches to monitor the changes seen during ZGA.

General

Imprint:	HumanaPress
Country of origin:	United States
Series:	Methods in Molecular Biology, 1605
Release date:	June 2018
First published:	2017
Editors:	Kiho Lee
Dimensions:	254 x 178mm (L x W)
Format:	Paperback
Pages:	272
Edition:	Softcover reprint of the original 1st ed. 2017
ISBN-13:	978-1-4939-8359-9
Categories:	Books > Medicine > Pre-clinical medicine: basic sciences > Medical genetics
LSN:	1-4939-8359-8
Barcode:	9781493983599

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