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Affinity Biosensors - Techniques and Protocols (Paperback, 1998)
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Affinity Biosensors - Techniques and Protocols (Paperback, 1998)
Series: Methods in Biotechnology, 7
Expected to ship within 10 - 15 working days
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The frequency of reports concemmg the interface of biological reco-
tion elements to signal transduction technologies has risen
dramatically over the last decade. Because any one of a wide
variety of biological recognition elements (e. g. , antibodies,
receptors, DNA, microorganisms, or enzymes) can theoretically be
interfaced with any one of a wide variety of signal transducers (e.
g. , optical, electrochemical, thermal, or acoustic), the potential
range of devices and techniques can be bewildering. The purpose of
this volume and the previous volume in this series is to provide a
basic reference and startmg point for investigators in academics,
mdustry, and government to begin or expand their biosensors
research. This volume, Methods in Biotechnology vol. 7: Affinity
Biosensors: Techniques and Protocols, describes a variety of
classical and emerging transduction technologies that have been
interfaced to bioaffinity elements (e. g. , antibodies and
receptors). Some of the reasons for the expansion in the use of
affinity-based biosensors include both advances in signal
transduction technologies (e. g. , fiber optics, microelectromcs,
and microfabrication) and the availability of bioafflmty elements.
More specifically, with respect to biological recognttion elements,
commercially and noncommercially produced antibodies directed
toward a variety of analytes have become widely available. In
addition, te- niques for the purification and stabilization of
receptors have also significantly improved. As a result of these
recent advances in the field, biosensors research and development
projects are being pursued by mvestigators from a wide range of
disciplines.
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