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Books > Science & Mathematics > Biology, life sciences > Cellular biology
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Cardiomyocytes - Active Players in Cardiac Disease (Hardcover, 1st ed. 2016)
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Cardiomyocytes - Active Players in Cardiac Disease (Hardcover, 1st ed. 2016)
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This book summarizes our current understanding about the biology
and patho-biology of cardiomyocytes and depicts common techniques
for the study of these cells. The book is divided into two parts;
the first part provides insight into role and function of
cardiomyocytes under normal conditions and describes embryogenesis
and differentiation, in the second part the role of cardiomyocytes
in aging and disease is discussed and cellular responses under
stress conditions illustrated. Cardiomyocytes represent the main
mass of the heart, and cellular malfunction directly modifies heart
function leading to subsequent heart failure. As such,
cardiomyocytes are causative involved in the main reasons of heart
failure, such as post-infarct remodeling, hypertensive heart
disease, idiopathic heart failure, and interactions with other
co-morbidities such as diabetes. On the other hand, cardiomyocytes
are necessarily target of therapy. Therefore, a precise
understanding of cardiomyocytes biology is a pre-requisite for
proper disease treatment and evidence based medicine. The book is
written for cell biologists, pharmacologists and biomedical
researchers specialized in cardiac and vascular biology.
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