Providing the most current information on the function of human
growth hormone (GH) and the consequences of its deficiency, this
practical yet comprehensive text is divided into three sections.
Part one describes the mechanisms of GH secretion and action,
including the physiology of GH and its regulation by sex steroids
and thyroid hormones, the effects of both under nutrition and
obesity on GH secretion, and the metabolic effects of human
recombinant GH therapy. The second section covers diagnostic
strategies and tests for GH deficiency in both children and adults,
including MRI of the pituitary. The final section describes the
different etiologies of GH deficiency, from molecular mechanisms
and gene abnormalities to cranial radiation and traumatic brain
injury, along with syndromes related to this deficiency. Presenting
underlying mechanisms and pathologies, as well as diagnostic
methods, Growth Hormone Deficiency will provide the most up-to-date
essential information and evidence on this condition for the
clinical endocrinologist.
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