Directed Evolution of the Aspergillus niger Epoxide Hydrolase (Paperback)

Darwinian Evolution of an enzyme You might wonder, whats this Genetic Evolution of a biocatalyst, scientifically known as "directed evolution," has emerged in last decade thanks to great advances in molecular biology as a very powerful tool to genetically "manipulate" an enzyme, either to improve enzyme properties, to switch the selectivity or to create a completely new catalyst. Epoxides are versatile building blocks for natural product synthesis. Quoting Prof. Seebach: If carbonyl compounds have been said to be virtually the backbone of organic synthesis, the epoxides correspond to at least one of the main muscles, this emphasized the importance of these compounds. Epoxide hydrolases are useful biocatalysts to obtain optically enriched epoxides. This work applied directed evolution as a strategy to improve the enantioselectivity of an epoxide hydrolase. Different selection and screening methods were established... What about the final result? Take a look, you will find out!

General

Imprint:	VDM Verlag Dr. Mueller E.K.
Country of origin:	Germany
Release date:	October 2008
First published:	October 2008
Authors:	Li-Wen Wang
Dimensions:	229 x 152 x 6mm (L x W x T)
Format:	Paperback - Trade
Pages:	104
ISBN-13:	978-3-639-06015-7
Categories:	Books > Professional & Technical > Biochemical engineering > General Books > Professional & Technical > Industrial chemistry & manufacturing technologies > Industrial chemistry > Chemical engineering
LSN:	3-639-06015-6
Barcode:	9783639060157

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