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Books > Medicine > Pre-clinical medicine: basic sciences > Physiology
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Cardiovascular Responses to Exercise (Paperback)
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Cardiovascular Responses to Exercise (Paperback)
Series: Colloquium Series on Integrated Systems Physiology
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Exercise is the act of increasing metabolic rate for the purpose of
enhancing physical fitness. Exercise can be one of the most
stressful physiological responses that the body undertakes. With
exercise, there are increases in metabolic rate, heart rate, blood
flow (hyperemia), respiration, and heat production. The increased
metabolic requirement during exercise is well met by an increased
blood flow (functional hyperemia) and oxygen supply to the
exercising tissue, which is regulated by multiple local and
systemic mechanisms. The local mechanisms (factors) are responsible
for mediating the muscle homeostasis and vascular conductance to
match the increased metabolic requirement, whereas the systemic
mechanisms are responsible for the maintenance of blood pressure
and global cardiovascular homeostasis, including the increase in
and redistribution of cardiac output, which is mainly mediated by
sympathetic activation. For instance, the substantial decreases in
vascular resistance and resultant large increase in blood flow
during exercise require higher blood pressure and more cardiac
output, such that the metabolically active muscle can be perfused
with adequate blood flow. This book will provide an overview of the
cardiovascular responses to exercise under physiological conditions
as well as some pathological circumstances.
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