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Philosophy of Cancer - A Dynamic and Relational View (Hardcover, 1st ed. 2016) Loot Price: R3,600
Discovery Miles 36 000
Philosophy of Cancer - A Dynamic and Relational View (Hardcover, 1st ed. 2016): Marta Bertolaso

Philosophy of Cancer - A Dynamic and Relational View (Hardcover, 1st ed. 2016)

Marta Bertolaso

Series: History, Philosophy and Theory of the Life Sciences, 18

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Loot Price R3,600 Discovery Miles 36 000 | Repayment Terms: R337 pm x 12*

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Since the 1970s, the origin of cancer is being explored from the point of view of the Somatic Mutation Theory (SMT), focusing on genetic mutations and clonal expansion of somatic cells. As cancer research expanded in several directions, the dominant focus on cells remained steady, but the classes of genes and the kinds of extra-genetic factors that were shown to have causal relevance in the onset of cancer multiplied. The wild heterogeneity of cancer-related mutations and phenotypes, along with the increasing complication of models, led to an oscillation between the hectic search of 'the' few key factors that cause cancer and the discouragement in face of a seeming 'endless complexity'. To tame this complexity, cancer research started to avail itself of the tools that were being developed by Systems Biology. At the same time, anti-reductionist voices began claiming that cancer research was stuck in a sterile research paradigm. This alternative discourse even gave birth to an alternative theory: the Tissue Organization Field Theory (TOFT). A deeper philosophical analysis shows limits and possibilities of reductionist and anti-reductionist positions and of their polarization. This book demonstrates that a radical philosophical reflection is necessary to drive cancer research out of its impasses. At the very least, this will be a reflection on the assumptions of different kinds of cancer research, on the implications of what cancer research has been discovering over 40 years and more, on a view of scientific practice that is most able to make sense of the cognitive and social conflicts that are seen in the scientific community (and in its results), and, finally, on the nature of living entities with which we entertain this fascinating epistemological dance that we call scientific research. The proposed Dynamic and Relational View of carcinogenesis is a starting point in all these directions.

General

Imprint: Springer
Country of origin: Netherlands
Series: History, Philosophy and Theory of the Life Sciences, 18
Release date: September 2016
First published: 2016
Authors: Marta Bertolaso
Dimensions: 235 x 155 x 17mm (L x W x T)
Format: Hardcover
Pages: 190
Edition: 1st ed. 2016
ISBN-13: 978-9402408638
Categories: Books > Science & Mathematics > Science: general issues > Philosophy of science
Books > Science & Mathematics > Biology, life sciences > Cellular biology > General
Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General
LSN: 9402408630
Barcode: 9789402408638

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