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Books > Medicine > Clinical & internal medicine > Paediatric medicine
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Retinoblastoma (Hardcover, 2010 ed.)
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Retinoblastoma (Hardcover, 2010 ed.)
Series: Pediatric Oncology
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Although rare, retinoblastoma has been at the fore- fortunate;
while in the developed world eye preser- front of cancer research
and treatment for the last tion has become a priority, developing
countries c- three decades. The two-hit hypothesis of oncogenesis
tinue to face delays in diagnosis, poor access to care, proposed by
Alfred Knudson provided the conceptual and suboptimal treatment -
the problem in the less framework for tumor suppressor gene
research and developed world is cure. led to the discovery of the
retinoblastoma pathway as In this book, we have invited a team of
experts to a key element in cancer development. More recently,
address all those important aspects of retinoblastoma the treatment
of children with retinoblastoma has also research and therapy -
from biology to epidemiology provided a model for modern approach
to the can- to treatment. We hope that in subsequent editions we
cer patient; state of the art retinoblastoma treatment will be able
to continue to provide updates on such can only be conceived in the
context of the multidis- exciting subjects.
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