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Bone Morphogenetic Proteins - Methods and Protocols (Hardcover, 1st ed. 2019)
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Bone Morphogenetic Proteins - Methods and Protocols (Hardcover, 1st ed. 2019)
Series: Methods in Molecular Biology, 1891
Expected to ship within 12 - 17 working days
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This volume provides methods to study bone morphogenetic proteins
(BMPs) and BMP modulators in cell culture, in both invertebrate and
vertebrate animal models, and for therapeutic applications.
Chapters guide the reader in the use of primary and immortalized
cell lines, methodologies that exploit transcription and receptor
mechanisms, newly developed animal models using nematodes, flies,
amphioxus, frogs, zebrafish, and genetically engineered mice, and
pre-clinical approaches to understanding BMP function in bone
regeneration, heterotopic ossification, and cancers. Written in the
highly successful Methods in Molecular Biology series format,
chapters include introductions to their respective topics, lists of
the necessary materials and reagents, step-by-step, readily
reproducible laboratory protocols, and key tips on troubleshooting
and avoiding known pitfalls. Authoritative and cutting-edge, Bone
Morphogenetic Proteins: Methods and Protocols aims to ensure
successful results in the further study of this vital field.
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