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Painful Sex Associated with Menopause - Interpreting FDA Warnings When Choosing a Treatment for Dyspareunia (Hardcover)
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Painful Sex Associated with Menopause - Interpreting FDA Warnings When Choosing a Treatment for Dyspareunia (Hardcover)
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Dyspareunia, or painful sexual intercourse, associated with
menopause has been a taboo subject for decades. During the past
year, postmenopausal women have been saturated with print and
television advertisements regarding two prescription treatments for
painful sex associated with menopause. This book is intended to
elucidate in understandable terms the two prescription options
currently available for the treatment of dyspareunia, Premarin (R)
(conjugated equine estrogens) Vaginal Cream and Osphena
(ospemifene) oral tablets. Premarin (R) is a cocktail of hormones
isolated from the urine of pregnant horses that was originally
approved by the U.S. Food and Drug Administration (FDA) for the
treatment of menopausal symptoms in 1942. Today, Premarin (R)
remains the most commonly prescribed hormone replacement therapy
(HRT). Osphena is a synthetic non-estrogen drug approved in 2013
that is classified as a selective estrogen receptor modulator
(SERM). Other SERMs approved by the FDA include tamoxifen for
breast cancer treatment and prevention, and Evista (R) (raloxifene)
for the prevention of postmenopausal osteoporosis and reducing the
risk of breast cancer. The FDA is required to educate the public
about the benefits and risks of prescription drugs. Unfortunately,
these messages are not always clear. We discuss, in understandable
terms, the benefits and risks of Premarin (R) Vaginal Cream and
Osphena oral tablets as seen in media advertisements, boxed
warnings and package inserts. Throughout this book, we discuss the
history of these two treatment options for dyspareunia and the
future research intended to improve upon hormone replacement
therapy for postmenopausal women.
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