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Books > Science & Mathematics > Biology, life sciences > Cellular biology
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Advances in Respiratory Cancerogenesis (Hardcover, 1st ed. 2016)
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Advances in Respiratory Cancerogenesis (Hardcover, 1st ed. 2016)
Series: Advances in Experimental Medicine and Biology, 911
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Lung cancer is the leading cause of mortality worldwide, with a low
survival rate. Carcinogenesis generally requires a constellation of
entwined steps, involving both innate cellular and environmental
factors. This book shares the updated knowledge on the origin and
development of cancer through genotypic changes which upset the
physiological balance between cell proliferation, differentiation,
growth control, and apoptosis. The emphasis is put on the role of
microRNA proteins involved in the cellular processes above
outlined. Cognitive changes, related to dysregulated cellular
mechanisms in cancer cells, as yet unchartered area of research,
also are tackled. A better understanding of the molecular and
cellular biology of lung cancer is the key source of breakthroughs
in the diagnosis and prognosis, and finding more effective
therapies that target specific mutations. The book provides a
source of current facts and trends in clinical research and
practice. It will be of interest to clinicians, researchers, and
other medical professionals.
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