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Regulation of Signal Transduction in Human Cell Research (Hardcover, 1st ed. 2018)
Loot Price: R2,915
Discovery Miles 29 150
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Regulation of Signal Transduction in Human Cell Research (Hardcover, 1st ed. 2018)
Series: Current Human Cell Research and Applications
Expected to ship within 10 - 15 working days
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This volume focuses on the relationship between the regulation of
signal transduction and disease mechanisms, and discusses how the
dysregulation of intracellular signals cause diseases, cell death,
carcinogenesis, and other disorders. Growth, survival,
transformation, and metabolic activities at the cellular level are
regulated by various intracellular signal transduction pathways.
Sources that stimulate intracellular signals include intracellular
stresses and signal regulators/modulators, as well as extracellular
growth factors. Recent studies on signal transduction analysis
using animal and human cell lines have revealed how the
intracellular signals are regulated and why their dysregulation
leads to pathological states such as tumorigenesis, metabolic
diseases, cell death, and so on. This book highlights several
important key molecules and intracellular signaling pathways such
as microRNA, the TGF-beta signaling pathway, the Wnt signaling
pathway and MET signaling pathway as topical and highly relevant
issues in human cell research related to signal transduction. In
addition to assessing the pathogenic role of these signaling
pathways, it focuses on the molecular design of small molecule
regulators/inhibitors of said pathways, one of the most important
approaches in this area. This book offers a valuable guide, helping
not only research scientists but also clinicians to understand how
the dysregulation of intracellular signals leads to diseases.
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