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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology

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Regulation of Signal Transduction in Human Cell Research (Hardcover, 1st ed. 2018) Loot Price: R2,915
Discovery Miles 29 150
Regulation of Signal Transduction in Human Cell Research (Hardcover, 1st ed. 2018): Nariyoshi Shinomiya, Hiroaki Kataoka, Qian...

Regulation of Signal Transduction in Human Cell Research (Hardcover, 1st ed. 2018)

Nariyoshi Shinomiya, Hiroaki Kataoka, Qian Xie

Series: Current Human Cell Research and Applications

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Loot Price R2,915 Discovery Miles 29 150 | Repayment Terms: R273 pm x 12*

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This volume focuses on the relationship between the regulation of signal transduction and disease mechanisms, and discusses how the dysregulation of intracellular signals cause diseases, cell death, carcinogenesis, and other disorders. Growth, survival, transformation, and metabolic activities at the cellular level are regulated by various intracellular signal transduction pathways. Sources that stimulate intracellular signals include intracellular stresses and signal regulators/modulators, as well as extracellular growth factors. Recent studies on signal transduction analysis using animal and human cell lines have revealed how the intracellular signals are regulated and why their dysregulation leads to pathological states such as tumorigenesis, metabolic diseases, cell death, and so on. This book highlights several important key molecules and intracellular signaling pathways such as microRNA, the TGF-beta signaling pathway, the Wnt signaling pathway and MET signaling pathway as topical and highly relevant issues in human cell research related to signal transduction. In addition to assessing the pathogenic role of these signaling pathways, it focuses on the molecular design of small molecule regulators/inhibitors of said pathways, one of the most important approaches in this area. This book offers a valuable guide, helping not only research scientists but also clinicians to understand how the dysregulation of intracellular signals leads to diseases.

General

Imprint: Springer Verlag, Singapore
Country of origin: Singapore
Series: Current Human Cell Research and Applications
Release date: March 2018
First published: 2018
Editors: Nariyoshi Shinomiya • Hiroaki Kataoka • Qian Xie
Dimensions: 235 x 155mm (L x W)
Format: Hardcover
Pages: 218
Edition: 1st ed. 2018
ISBN-13: 978-981-10-7295-6
Categories: Books > Science & Mathematics > Biology, life sciences > Biochemistry > General
Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General
LSN: 981-10-7295-7
Barcode: 9789811072956

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