This book focuses on the functional significance of targeting
apoptosis for the treatment of prostate cancer. New concepts on the
challenges relating to the development of resistance by
androgen-independent tumors are introduced, in terms of the
contribution of anoikis and cross-talk of androgens with key growth
factor signaling pathways. This volume also provides insightful
discussion on the exploitation of the apoptotic and angiogenic
synergism towards complete eradication of prostate tumors. Last but
not least, it includes reflections on the drug development
challenge based on the analysis of data from existing clinical
trials.
General
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