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In Vivo MR Techniques in Drug Discovery and Development (Hardcover)
Loot Price: R5,584
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In Vivo MR Techniques in Drug Discovery and Development (Hardcover)
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Imaging technologies are receiving much attention in the
pharmaceutical industry because of their potential for accelerating
drug discovery and development. Magnetic Resonance (MR) Imaging is
one of the principal modalities since it allows anatomical,
functional, metabolic, and to a certain extent even target-related
information to be gathered in vivo at high resolution, favoring the
characterization of a disease state and the corresponding drug
intervention. The non-invasiveness of MR strengthens the link
between preclinical and clinical pharmaceutical research,
contributing to improve the characterization of compound effects in
early stages of the discovery process in order to increase the
chances of success in later phases of drug development. Edited by a
leading researcher in MR technology, with contributions from
foremost experts in academia and the pharmaceutical industry, this
title illustrates the use of MR techniques throughout the drug
discovery and development process, from target identification and
validation to clinical studies. Numerous chapters focus on
individual disease areas, including neurological, cardiac, and
pulmonary disorders, cancer studies, diabetes, arthritis, solid
organ transplantation, and stem cell-based therapies, showing that
different imaging solutions are needed for specific organs.
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