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Books > Medicine > Pre-clinical medicine: basic sciences > Physiology
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Matrix Proteases in Health and Disease (Hardcover)
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Matrix Proteases in Health and Disease (Hardcover)
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Presenting a comprehensive overview of the multifaceted field of
proteases in the extracellular matrix environment, this reference
focuses on the recently elucidated functions of complex proteolytic
systems in physiological and pathological tissue remodeling. The
proteases treated include both serine proteases such as plasminogen
activators and TTSPs, metalloproteases such as MMPs and ADAMS and
cysteine protease cathepsins. The text specifically addresses the
role of extracellular proteases in cancer cell invasion, stroke and
infectious diseases, describing the basic biochemistry behind these
disease states, as well as therapeutic strategies based on protease
inhibition. With its trans-disciplinary scope, this reference
bridges the gap between fundamental research and biomedical and
pharmaceutical application, making this required reading for basic
and applied scientists in the molecular life sciences.
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