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Vitamin D in Chronic Kidney Disease (Hardcover, 1st ed. 2016)
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Vitamin D in Chronic Kidney Disease (Hardcover, 1st ed. 2016)
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Vitamin D deficiency, circulating levels lower than 15 ng/ml, is an
epidemic disease worldwide with more than a billion people
suffering of it in the beginning of the 21-century. Besides its
impact on mineral and bone metabolism, these low vitamin D levels
are also associated with a diversity of non-skeletal complications,
among them cardiovascular disease, diabetes mellitus, multiple
sclerosis, cancer, tuberculosis, and immune system dysfunction.
Chronic Kidney Disease is also a very common disease, affecting
more than 10% of the world population, ranging from stage 1 to
stage 5 before dialysis. Approximately 1% of the population in
industrialized countries is affected by end-stage renal disease
(ESRD), needing a renal replacement therapy either hemodialysis or
peritoneal dialysis, and ultimately by renal transplantation. Those
CKD patients are more susceptible to exhibit reduced vitamin D
stocks. Consequently, more than eighty percent of CKD patients have
either insufficient or deficient vitamin D levels for multiple
reasons.
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