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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology

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Developments in T Cell Based Cancer Immunotherapies (Hardcover, 1st ed. 2015) Loot Price: R5,465
Discovery Miles 54 650
Developments in T Cell Based Cancer Immunotherapies (Hardcover, 1st ed. 2015): Paolo A. Ascierto, David F. Stroncek, Ena Wang

Developments in T Cell Based Cancer Immunotherapies (Hardcover, 1st ed. 2015)

Paolo A. Ascierto, David F. Stroncek, Ena Wang

Series: Cancer Drug Discovery and Development

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Loot Price R5,465 Discovery Miles 54 650 | Repayment Terms: R512 pm x 12*

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This volume illustrates the salient aspects of cancer biology relevant to the successful implementation of immunotherapy. Topics include enhancement of antigen-specific immune responses by anti-cancer vaccines, modulation of the function of T cells within the tumor microenvironment, and the effects of genetic, epigenetic, developmental, and environmental determinants on T cell function. Other topics covered include the ex vivo expansion of T or other immune cells and their genetic modification or reprogramming to increase their ability to survive and expand when adoptively transferred back to the patients. Specific attention is devoted to the genetic manipulation of T cells through the introduction of re-directed T cell receptors, chimeric antibody receptors, and other genetic manipulation aimed at improving their effectiveness as anti-cancer agents. Furthermore, the revolutionary role of checkpoint inhibitors and their potential in combination with other immunotherapeutic approaches or with standard chemo and radiation therapy are extensively discussed.

General

Imprint: Birkhauser Verlag AG
Country of origin: Switzerland
Series: Cancer Drug Discovery and Development
Release date: December 2015
First published: 2015
Editors: Paolo A. Ascierto • David F. Stroncek • Ena Wang
Dimensions: 235 x 155 x 23mm (L x W x T)
Format: Hardcover
Pages: 305
Edition: 1st ed. 2015
ISBN-13: 978-3-319-21166-4
Categories: Books > Medicine > General issues > Medical equipment & techniques > Medical research
Books > Medicine > Other branches of medicine > Pharmacology > General
Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General
Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology > General
LSN: 3-319-21166-8
Barcode: 9783319211664

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