Synthesis & Evaluation of 2&6-Substituted 4h-Chromen-4-One Derivatives (Paperback)

The present investigation is concerned with synthesis of new 2 and 6 - substituted 4H-chromen-4-One derivatives with the objectives of discovering novel and potent anti-inflammatory agents and anti-oxidants. The results of anti-inflammatory activity were revealed that the compound has indole 2 substitution with 4-nitrophenyl amino methyl (at 6th position) on 4H- chromen-4-one having more anti-inflammatory activity as compared to other substituent's. While, indole 2 substituted 4-methoxy phenyl amino methyl (at 6th position) 4H-chromen-4-one showed outperformed anti-oxidant activity in different anti-oxidant model as compared to other substituent's. The all newly synthesized compounds displayed moderate to potent anti-inflammatory and anti-oxidant activity and has therapeutic potential in combating this devastating inflammatory and oxidative condition of the body, might be deserve promising substances for further in vivo evaluation as anti-inflammatory and anti-oxidant properties. However the anti-inflammatory activity is not related to antioxidant potential.

General

Imprint:	Lap Lambert Academic Publishing
Country of origin:	United States
Release date:	February 2013
First published:	February 2013
Authors:	Patel Chirag J. • Sagar Gali Vidya • Faldu Poonam R.
Dimensions:	229 x 152 x 6mm (L x W x T)
Format:	Paperback - Trade
Pages:	100
ISBN-13:	978-3-659-34549-4
Categories:	Books > Medicine > Other branches of medicine > Pharmacology > General
LSN:	3-659-34549-0
Barcode:	9783659345494

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